August 11, 2022

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Ukko Secures $40 Million in Sequence B Funding Led by Leaps by Bayer to Prevail over Food stuff Allergies and Sensitivities

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PALO ALTO, Calif., TEL AVIV, Israel and LEVERKUSEN, Germany, Jan. 27, 2021 /PRNewswire/ — Ukko, a biotech firm with the mission to remove foods allergies and sensitivities, currently introduced $40 million in new Collection B funding. Ukko harnesses synthetic intelligence (AI) and protein engineering to produce more healthy food stuff and therapies for foods allergy symptoms. The new funding will permit Ukko to enter scientific trials with its investigational therapeutic for peanut allergy. It will also accelerate development of Ukko’s gluten that is made for persons with celiac and other gluten sensitivities. The spherical was led by Leaps by Bayer – the influence expense arm of Bayer – and was joined by Continental Grain Enterprise, PeakBridge Ventures, Skyviews Lifetime Science and Fall Line Cash, as effectively as current investors Khosla Ventures, Innovation Endeavors, and TIME Ventures, the investment decision fund of Marc Benioff.

Novel solution with AI-run platform

Ukko’s novel strategy takes advantage of a proprietary AI-powered platform that precisely engineers foods proteins to eliminate their allergenicity, although keeping their fantastic biochemical and dietary characteristics. The system utilizes patient samples, computational biology, immunology, and protein engineering to make proteins that do not cause the immune program.

“We are at a unique crossroads in the history of science,” claimed Prof. Yanay Ofran, Chairman and Co-founder of Ukko. “Big information lets us to recognize the underpinnings of food sensitivities. Computational equipment make it possible for us to specifically layout the proteins that make up our bodies and our foods. New genome modifying systems make it possible for us to rewrite DNA to produce these new proteins in dwelling cells. Ukko sits at the intersection of these breakthrough technologies, enabling us to redefine healthful food items at the molecular stage, based mostly on actual information.”

Ukko has already crafted a person of the greatest clinically-validated molecular maps of food allergies, which unlocks vital info and lets the enterprise a loaded foundation for further more innovation. Ukko has also generated promising information, dependent on individual samples, that suggests the company’s investigational peanut and gluten proteins do not result in allergic reactions responses in the immune method of sufferers.

“We are at the forefront of a revolution. Pharma and the foodstuff sector will redefine how they believe about their items and missions,” claimed Anat Binur, CEO and Co-Founder of Ukko. “Hundreds of tens of millions of men and women about the world suffer from foodstuff allergies and industry experts see it as a worldwide epidemic. Ending food allergy is important and is only the commencing. Ukko’s tech has the possible to leverage science and human info to redesign our foodstuff and drugs.”

Improved gluten proteins and treatment for peanut allergy

Ukko has a holistic foods-to-treatment tactic to solving meals allergy symptoms and sensitivities. On the foodstuff side, Ukko is performing on enhanced gluten proteins that are specifically intended for people today with celiac and other gluten sensitivities, which enables bakers, food items corporations, and house cooks to make tasty bread, pizza, pasta, and baked items that everyone can try to eat. On the therapeutic aspect, Ukko is making use of its protein layout platform to produce a new and promising investigational treatment for peanut allergy. Ukko’s upcoming pipeline features options to tackle supplemental important food stuff allergens.

“Ukko’s investigative methods to resolving allergies and food items sensitivities each from the foods aspect and the affected person therapeutics side have the risk of delivering massive advantages for humanity,” said Juergen Eckhardt, MD, Head of Leaps by Bayer, which was developed to generate basic breakthroughs in the fields of overall health and agriculture via new technologies. “One of the major problems we’re addressing via our Leaps investments is attempting to reverse autoimmune ailments, which have great impacts on the world’s foods systems and our well being techniques in each individual group close to the globe. We are very pleased to lead this financial commitment in Ukko and assist solve the most important allergy symptoms and meals sensitivities. It is a good in good shape to our international leadership position in the two health and nutrition.”

“I have been a witness to my patients’ growing urgency to find out a treatment for foodstuff allergic reactions. When there are incredible breakthroughs coming from the investigate and biotech worlds, basic safety continues to be a major hurdle. Ukko’s endeavours to remedy these challenges for allergies and sensitivities is one of the most promising and thrilling strategies I have seen” stated Prof. Lynda Schneider, Director of the Allergy Software at Boston Children’s Clinic and Professor of Pediatrics at Harvard Health-related University.

Amount of folks struggling food items allergies to climb in the coming several years

Hundreds of hundreds of thousands of people close to the planet undergo from food allergic reactions and industry experts predict the numbers will continue to climb in the coming many years. In the U.S. by itself, a single in 13 small children has food allergy symptoms (about two in every single classroom) and every single 3 minutes a meals allergy reaction sends another person to the unexpected emergency area. The incidence of celiac disorder has been doubling every 15 years and – even at that level of progress – more than 80% of people stay undiagnosed, leaving these folks with greater threat for acquiring other significant disorders like anemia or even most cancers. Economically, foods allergy symptoms and sensitivities charge a lot more than $25 billion[1] every single year in the U.S. by yourself and position enormous strain on family members, communities, the healthcare system, and the ag and foods industries.

Ukko has formed an Advisory Board that includes some of the world’s prime clinical experts in foodstuff allergy and sensitivities, and experts in foodstuff and agriculture innovation. The Advisory Board supports the firm on the coverage, small business method, science, and clinical factors of Ukko’s function. Some of Ukko’s advisors consist of Bernhard Van Lengerich, Previous Main Science Officer & Vice President for Technological know-how Approach at Typical Mills Ann M. Veneman, Former US Secretary of Agriculture Dr. Wesley A. Burks, Dean and CEO of the Univ. of North Carolina (UNC) School of Drugs and UNC Health and fitness Dr. Edwin Kim, Affiliate Professor, Allergy & Immunology Program Director, UNC Foodstuff Allergy Initiative Dr. Kari Nadeau, Director of the Sean N. Parker Heart for Allergy and Bronchial asthma Investigate at Stanford College Prof. Lynda Schneider, Director, Allergy Plan Boston Children’s Medical center Professor of Pediatrics Harvard Health-related University and Prof. Raanan Shamir, Chairman, Institute of Gastroenterology, Nutrition and Liver Illnesses at Schneider Children’s Health care Centre of Israel.

[1] https://www.foodallergy.org/sources/psychosocial-impact-meals-allergic reactions

About Ukko:

Ukko is a biotech enterprise with the mission to eradicate food allergy symptoms and sensitivities. Ukko uses a proprietary AI-pushed protein engineering system that will allow the enterprise to acquire more healthy meals and new varieties of therapeutics. Hundreds of millions of people today undergo from foods allergy symptoms — a difficulty experts connect with an epidemic. Ukko is applying its engineering system to produce an investigational therapeutic for peanut allergy symptoms and an improved gluten for people with gluten sensitivities which includes celiac that will enable creating healthy and wonderful foods. The corporation is co-started by CEO Anat Binur, retains a PhD from MIT and an MPH from Columbia, together with the company’s Chairman, Yanay Ofran, who holds a PhD from Columbia College and is considered a major professional in computational biology and who is also a professor at Bar Ilan College in Tel Aviv. Ukko is backed by some of the world’s leading investors in food, pharma, ag, and engineering. The company’s Advisory Board incorporates renowned allergy researchers and physicians, as well as executives and policymakers from the foodstuff and agriculture industries. Ukko is committed to working carefully with the U.S. Foodstuff and Drug Administration and adhering to all applicable laws prior to promoting any of its meals or therapeutic merchandise. For extra details, go to www.ukko.us.

About Bayer and Leaps by Bayer:

Bayer is a international enterprise with core competencies in the daily life science fields of health and fitness care and nutrition. Its items and solutions are created to profit persons by supporting endeavours to prevail over the big challenges presented by a increasing and getting older international population. At the same time, the Group aims to enhance its earning electric power and make worth as a result of innovation and development. Bayer is committed to the ideas of sustainable progress, and the Bayer model stands for rely on, trustworthiness and quality all over the world. In fiscal 2019, the Team utilized around 104,000 people today and experienced profits of 43.5 billion euros. Funds expenditures amounted to 2.9 billion euros, R&D charges to 5.3 billion euros. For extra data, go to www.bayer.com.

Leaps by Bayer, a device of Bayer AG, qualified prospects affect investments into alternatives to some of today’s major difficulties in health and agriculture. The expense portfolio contains far more than 30 companies. They are all doing work on perhaps breakthrough technologies to triumph over some precise challenges this sort of as, e.g. regenerating dropped tissue operate, lowering the environmental impression of agriculture, stopping or curing cancer, and many others. For a lot more data, go to leaps.bayer.com

Speak to for media inquiries (Bayer):

Carly Scaduto,
cellular phone +1 314 439 6978
Electronic mail: [email protected]

Alexander Hennig,
cellular phone +49 175 30 89 736
Electronic mail: [email protected]

Get hold of for media inquiries (Ukko):

Mollie Starr,
cell phone +1 415 602 7043
Electronic mail: [email protected]

Ahead-On the lookout Statements

This release may perhaps incorporate ahead-searching statements centered on present assumptions and forecasts produced by Bayer management. Different recognized and unfamiliar threats, uncertainties and other components could lead to content variances in between the genuine long run results, economic condition, enhancement or general performance of the organization and the estimates given in this article. These aspects include all those talked over in Bayer’s public stories which are accessible on the Bayer web page at www.bayer.com. The corporation assumes no legal responsibility by any means to update these ahead-on the lookout statements or to conform them to long run situations or developments.

Check out first content: http://www.prnewswire.com/information-releases/ukko-secures-40-million-in-collection-b-funding-led-by-leaps-by-bayer-to-prevail over-foodstuff-allergy symptoms-and-sensitivities-301215923.html

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